Future University In Egypt (FUE)

Staff Research

Paper Title :
Author : Hayam Lotfy
CoAuthors : Nevin Erk, Yasmin Rostom
Source : Spectrochemica Acta Part A: Molecular and Biomolecular Spectroscopy
Date of Publication : 07/2019
Abstract : Spectral numerical factor techniques have been developed for quantification of a new pharmaceutical combination. Five simple, fast and accurate spectrophotometric methods using spectral factor manipulation have been tested and validated so as to determine quantitatively a new fixed-dose combination tablet containing both amlodipine besylate (ADB) and rosuvastatin calcium (ROS). Namely, these methods are induced dual wavelength, absorbance correction, absorbance subtraction, amplitude correction and advanced amplitude subtraction. Their corresponding spectral factors are equality, absorption, absorbance, amplitude and unity factor, respectively. Calibration curves of ADB and ROS were set up for all the previously mentioned methods under the optimum conditions in a concentration range of 3.0–21.0 μg/mL with correlation coefficients ≥0.9990. Selectivity was calculated by analyzing laboratory-prepared synthetic blends of the cited drugs. A comparative study between these methods and the reported ones has been carried out statistically forming a judgment that the difference between both results is totally insignificant. Actually, the suggested spectral factor technique is so effective for use in routine laboratory essay owing to its simplicity, rapidity and precision. Generally, the proposed factor procedures have the ability to run smoothly without any interference from additives that may deteriorate analysis efficiency of a pharmaceutical combination
Download PDF
BACK
  • Research Centers

    With the growing emphasis on collaborative and interdisciplinary science, Research Centers have become indispensable to highly ranked universities. They gain their importance from the outstanding role they play in enhancing the academic activities, in general, and post graduate reputation and scientific ranking in particular. Realizing this fact, Future University in Egypt (FUE) have decided and allocated sufficient funds and infrastructure to establish FUE Research Center (FUERC) having the following vision, mission, and goals

    read more
  • Continuing Education

    Future University in Egypt’s Department of Continuing Education (DCE) is dedicated to bridging the gap between the capabilities

    read more
  • FUE Pharmaceutical Factory

    The Future Factory for Industrial Training’s (FFIT) aim is to be recognized for its unique training facility as well as its advanced techniques. As a result, we established a training pharmaceutical plant, that provides an actual simulation of an industrial atmosphere with the processes and procedures that take place in the manufacturing world.

    read more
  • FUE Dental Hospital

    FUE has maintained a highly reputable dental faculty over the years, therefore the development of the Dental Hospital is a step towards the FUE goal of providing the best dental academic programs

    read more
Community service unit at Faculty of Pharmaceutical Sciences and Pharmaceutical Industries, launches Q&A about Covid-19.

Community service unit at Faculty of Pharmaceutical Sciences and Pharmaceutical Industries, launches Q&A about Covid-19.

COVID-19 Awareness
FUEscientificJournals

VISIT FUE

Take a step to<br>Future<br>For a better future

Address

End of 90th St., Fifth Settlement,
New Cairo, Egypt

Hotline

Inside Egypt: 16383 (16FUE)

Outside Egypt: +20216383, +2026186100

Copyright © 2023 [Future University in Egypt]. All rights reserved.